Toxicology
Seventh Wave provides consulting services in Preclinical Toxicology as an extension of our clients' research and development activities (consulting services). Our consulting scientists have extensive experience in preclinical safety evaluation of small to large molecules (chemical and pharmaceutical) and biotherapeutics in both small and large pharmaceutical settings. Using both our technical and strategic expertise, we have supported numerous successful lead optimization efforts and active Investigational New Drug applications across a wide range of therapeutic areas.
Toxicology studies at Seventh Wave are conducted in an FDA-inspected, AAALAC-accredited facility by AALAS-certified staff members. Toxicology studies may be conducted in rodents and non-rodents and with a variety of administration routes (In Vivo services). Clients may select from a standard study design to assess commonly investigated endpoints, or customize their study design to examine parameters of unique interest. Typical endpoints include: clinical observations, clinical pathology (hematology, serum chemistry, and coagulation parameters), histopathology, bioanalysis of plasma exposure samples, and toxicokinetics. Additional endpoints such as ophthalmic exams and ECG evaluation are also available. Seamless integration of our preclinical services (Bioanalysis, PK/ADME, Pathology) assures that the right studies are conducted to meet your timelines and project goals.